Key Benefits of Migraine Support Supplements

Harness the Power of Nutritional Support for Migraine

We know that migraine is so much more than a headache: It’s a complex neurological disease. That’s why our migraine support supplements are designed specifically for migraine, based on the research and clinical expertise of leading headache specialists at the Jefferson Headache Center.

We’ve put their insights to work and developed high-quality nutritional support to build your toolkit.

“Nutritional supplements are important for headache and migraine, but I have never felt confident in the accuracy of the claims made by most supplement manufacturers. So I worked with Care Tuner to create supplements I can trust and recommend to my patients.”

Dr. Stephen D. Silberstein
Co-Medical Director, Care Tuner
Director, Jefferson Headache Center

Certain supplements may positively impact living with migraine, including riboflavin (vitamin B2), coenzyme Q10, magnesium, butterbur, feverfew, and melatonin.

Picture of Magnesium supplement bottle with big lime green “M” on it, lime green gradient background with ingredients.


People living with migraine are often deficient in magnesium. The biggest downside of magnesium supplementation, however, is that some of its forms can result in stomach discomfort and upset. That’s why we developed a variety that is gentle on the stomach.

Picture of B2 supplement bottle with big blue “M” on it, blue gradient background with bowls of ingredients.


The vitamin Riboflavin, also known as B2, is an energy booster. It impacts the mitochondria—or energy factories—in each of our cells. Evidence also suggests a relationship between improper functioning of mitochondria and migraine, which is why headache researchers have taken a keen interest in vitamin B2.

Picture of Melatonin supplement bottle with big green “M” on it, green gradient background with ingredients.


Getting good quality sleep is the single most impactful lifestyle change to improve health with migraine. Melatonin is a popular natural sleep aid commonly used for insomnia and improving sleep.

Picture of CoQ10 supplement bottle with big green “M” on it, green gradient background with plant.


An antioxidant that cells need for growth and maintenance, coenzyme Q10 has been shown to decrease the frequency of headaches.

Picture of Petadolex Butterbur supplement bottle with big pink “M” on it, pink gradient background with plant.


Butterbur is a carefully processed plant extract that comes from the leaves and roots of the plant Petasites hybridus. It is known for its anti-inflammatory properties, which can help with migraine.

Picture of Feverfew supplement bottle with big purple “M” on it, purple gradient background with flowers.


This plant extract from the daisy family has a long history of use for its anti-inflammatory properties. Reducing inflammation can help control migraine.

For more answers

The National Institute of Health’s Office of Dietary Supplements is a great resource for tips on topics such as how to evaluate sources of healthcare information and a list of independent third-party organizations that quality test products.

Current concerns around migraine support supplements revolve around issues of purity, efficacy, and contamination due to the lack of rigorous industry standards. However, these concerns can be addressed by finding quality products from reputable manufacturers. Remember, it’s always a good idea to consult with your doctor to determine a plan before you start taking dietary supplements.

Take the Migraine Support Supplement Quiz

Find out which nutritional supports are best suited to manage your migraine symptoms and complement your care. Simply answer eight questions about your migraine and receive nutritional support recommendations based on your answers.

Take the Quiz

Find the Migraine Support Supplements That Are Right for You

We’ve built a world of support around your needs. Proven lifestyle changes, combined with targeted supplementation, can help you gain some relief from migraine symptoms, leading to overall better quality of life.

Take the Quiz

Available Subscription Service

Curated migraine care––bottled and delivered directly to you with an available subscription service. Once you know which migraine support supplements work best for you, head to our virtual store to browse products. Save 10% with a one-time purchase, or 20% with our monthly, auto-refill subscription service.

Our Virtual Store

The Care Tuner Guide to Migraine Nutrition

Research shows that the types of foods we eat, and when we eat, have an impact on our migraine. Our new eBook helps you understand the link between migraine and nutrition.

What Others Are Saying

“I’ve been taking Magnesium for four years. I’m now on my third month of Care Tuner’s magnesium and what a difference it makes from the drugstore brands.”

Lauren, 38